BETEN-50 is contraindicated in sinus bradycardia, heart block greater than first degree, cardiogenic shock, overt heart failure, untreated pheochromocytoma, and in those with known hypersensitivity to its ingredients. It is not to be advocated in acute myocardial infarction, when the heart failure is not promptly and effectively controlled by 80 mg of intravenous furosemide or equivalent therapy.

BETEN-50 is to be advocated with caution in congestive heart failure controlled by digitalis and / or diuretics. Continued depression of the myocardium with beta-blocking drugs such as atenolol, can lead to cardiac failure which must be promptly treated appropriately; if the cardiac failure persists, BETEN-50 must be withdrawn.

BETEN-50 is to be administered with caution in diabetes and thyrotoxicosis. In those with bronchospastic diseases, beta blockers are advocated only when other antihypertensives are not effective, or are not tolerated; in such instances, the lowest possible dose of BETEN-50 must be employed and stimulants must be made available.

It is not advisable to withdraw BETEN-50 prior to surgery, but care should be taken whilst advocating anesthetics that depress the heart.

BETEN-50 should not be preferably given during lactation and in children. It must be coadministered with care along with clonidine, indomethacin and other NSAIDs.

The adverse effects due to atenolol (BETEN-50) include gastrointestinal disturbances, central nervous system manifestations, bradycardia and other arrhythmias including heart block, cold extremities, postural hypotension, leg pain, wheezing / dyspnea and allergic reactions.

BETEN-50 can interact with verapamil, diltiazem, clonidine and prostaglandin synthase inhibitors such as indomethacin.

Hypertension: 1 BETEN-50 Tablet once daily; if no optimal response within 1-2 weeks, the dose can be increased to 2 BETEN-50 Tabs once daily.

BETEN-50 can be safely combined with other antihpertensives such as thiazides, prazosin and alpha-methyl dopa.

Angina Pectoris: 1 BETEN-50 Tablet once daily; if no optimal response within 1-2 weeks, the dose can be increased to 2 BETEN-50 Tabs once or twice daily.

Renal Dysfunction: 1 BETEN-50 Tablet once daily for creatinine clearance 15-35 ml/min/1.73 m; for those with creatinine clearance <15 ml/min/1.73 m it is optimal to advocate.