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Composition |
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Each tablet of FLANZEN-D contains: |
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Diclofenac sodium. . .50 mg |
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Serratiopeptidase. . .10 mg |
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Therapeutic Indications & Usage |
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FLANZEN-D is indicated for: |
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- Trauma Surgery: In sports injuries, sprains, laceration, fractures, dislocation and osteoarthritis etc.
- Surgery: To reduce post-operative edema at injection sites, internal tissue edema and inflammation caused at post-operative handling.
- Plastic Surgery: For diminishing post-operative edema, restoring micro-circulation at the site of graft and minimizing risk of graft rejection along with reduction in pain.
- Infections: Facilitating mucolysis in sinuses, ear cavities and coupled with anti-inflammatory activity in upper respiratory tract affections helps in faster resolution, better antimicrobial availability in infected tissues and faster cures.
- Dermatology: Particularly useful in acutely painful inflamed dermatoses.
- Dentistry: Helps better control over dental infections and inflammation.
- Obstetrics & Gynecology: The anti-inflammatory and anti-edema activity helps in resolution of post-partum hematomas, breast engorgements and pregnancy-related thrombophlebitis.
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Contraindications |
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FLANZEN-D is contraindicated in those who are hypersensitive to its ingredients. |
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Precaution & Warnings |
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Diclofenac (in FLANZEN-D) should be administered with caution in patients with acid-peptic disease, impaired renal or liver functions, blood dyscrasias, and in patients with hypersensitivity to aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs). |
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FLANZEN-D should be used in pregnant women and nursing mothers only if absolutely required. Data on safety and efficacy of diclofenac / serratiopeptidase (FLANZEN-D) in children is not adequate. |
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Since serratiopeptidase can enhance the action of anticoagulants, FLANZEN-D must be coadministered with due precaution. |
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Adverse Reactions |
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The most common side effects of diclofenac (in FLANZEN-D) are gastric pain, nausea, vomiting and diarrhea; rarely peptic ulcer and gastrointestinal bleeding occur. Infrequently, hypersensitivity reactions, malaise, change in appetite and weight, and eye disorders are possible due to diclofenac (in FLANZEN-D). Neurological reactions possible include headache, drowsiness, insomnia, irritability and mood disturbances. Diclofenac (in FLANZEN-D) can rarely cause hepatitis, renal dysfunction and blood dyscrasias. |
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Serratiopeptidase (in FLANZEN-D) can cause hypersensitivity reactions such as rash or redness, besides gastrointestinal side effects like anorexia, abdominal discomfort, nausea and vomiting. |
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Drug Interactions: |
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Concomitant use of diclofenac (in FLANZEN-D) with aspirin, methotrexate, digoxin, cyclosporin, triamterene and lithium is not advocated due to possibility of drug interaction. If coadministered with anticoagulants, serratiopeptidase (FLANZEN-D) can increase the anticoagulative action. |
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Recommended Dosage & Administration |
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ADULTS: 1 FLANZEN-D Tablet three times daily 1-2 hours after meals. |
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Presentations |
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FLANZEN-D Tablets: Blisters of 10s. |
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