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FEBRINIL:

 
         
       
       
           
           
       
         
         
       
        Composition
         
        Each tablet of FEBRINIL contains Paracetamol … 650 mg
Each 1 ml of FEBRINIL Drops contains: Paracetamol … 100 mg
Each 5ml of Febrinil 125 suspension contains Paracetamol IP 125 mg
        Each 5ml of Febrinil 250 suspension contains Paracetamol IP 250 mg.
Delicious strawberry flavour.
Each 1 ml of FEBRINIL Injection(2ml ampoules & 15ml vials) contains:
Paracetamol … 0.150 g , Benzyl alcohol (as preservative) … 2% v
         
         
        Therapeutic Indications & Usage:
         
        FEBRINIL is indicated for symptomatic relief of fever, temporary reduction of mild to moderate aches & pain associated with cold, flu, headache, muscular aches, sprains, overexertion and osteoarthritis. In children, FEBRINIL can be useful for simple pain and discomfort due to teething, immunizations and Tonsillectomy.
         
         
        Contraindications
         
        FEBRINIL is to be advocated with caution in liver & kidney damage; it should also be given with caution in those with alcohol dependence. FEBRINIL Injection especially must be advocated with caution in those with a creatinine clearance <30 ml/minute, chronic alcoholism, chronic malnutrition (low reserves of glutathione stores) and dehydration.
         
        In pregnancy and lactation FEBRINIL should be given only if strictly required. There is inadequate safety data for intramuscular (IM) / IV paracetamol (FEBRINIL Injection) use in neonates, infants and children <6 months of age.
         
        FEBRINIL should be coadministered with due precaution along with prokinetics such as metoclopramide, probenecid and cholestyramine.
         
        Adverse Reactions
         
        Side effects of paracetamol (FEBRINIL) are rare, and usually mild. Skin rashes and other hypersensitivity reactions could occur, and, on rare occasions, paracetamol could cause hematological changes. Pain at injection site can occur with FEBRINIL IM / IV.
         
         
        Drug Interaction
         
        Absorption of paracetamol from FEBRINIL is increased by concomitant metoclopramide, and such other agents. Probenecid can decrease it's clearance whilst cholestyramine diminishes absorption of paracetamol (FEBRINIL) when coadministered.
         
        Recommended Dosage & Administration
         
        Adults:
        1 FEBRINIL Tab / 1-2 tsf FEBRINIL Susp 4-6 hourly, or as prescribed.
Maximum up to 4 gm daily
         
        Children:
        Maximum of 4 doses per day. 6-12 yrs: ½-1 FEBRINIL Tab , 1-2tsf FEBRINIL Susp 4-6 hourly, or as prescribed.
         
        1-5 yrs: ¼-½ FEBRINIL Tab / ½-1 tsf FEBRINIL Susp 4-6 hourly, or as prescribed.
         
        3 mths-1 yr: ¼-½ tsf FEBRINIL Susp / 10-20 FEBRINIL Drops 4-6 hourly, or as prescribed.
         
        <3 mths: 10-15 mg/kg bodyweight as FEBRINIL Drops 4-6 hourly, or as prescribed.
         
        Parenteral
         
        Adults:
        2 ml FEBRINIL Injection IM / IV, or as prescribed. Minimum interval of 4 hours recommended in-between doses, and 6 hours in those with hepatic and / or renal impairment. Maximum of 1 gm up to 4 times daily.
         
        Children:
        (<33 kg): 15 mg/kg FEBRINIL Injection IM / IV up to 4 times daily as required, or as prescribed. Minimum interval of 6 hours recommended in-between doses. Maximum dose is 60 mg /kg per day.
         
        Neonates:
        7.5 mg/kg FEBRINIL Injection IM / IV up to 4 times daily as required, or as prescribed.
         
         
        Presentation
         
        FEBRINIL Tablets: Blisters of 10s.
FEBRINIL Drops: Vials of 15 ml.
FEBRINIL Injection: Ampoules of 2 ml; vials of 15 ml.
FEBRINIL 125 Suspension: bottle of 60ml
FEBRINIL 250 Suspension: bottle of 60ml
         
         
       
         
       
       
         
       
 

 

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