SIGMA PANTOTHENATE is indicated to gain resistance to stress, shock and allergies, plus protection against radiation-induced cellular damage. It also promotes wound healing and antibody formation. SIGMA PANTOTHENATE is advocated to manage vitamin B5 deficiency which may manifest as numbness in toes and painful burning of feet, headache, fatigue, insomnia, intestinal disturbances, impaired resistance. For acne, alcoholism, shingles and skin disorders, allergies, alopecia, premature graying of hair, burning feet syndrome, carpal tunnel syndrome, eripheral neuropathy, glossitis, stomatitis, hyperkinesis, hypoglycemia and insomnia SIGMA PANTOTHENATE is useful.

SIGMA PANTOTHENATE Injection [intramuscular (IM) / intravenous (IV)] is indicated after major abdominal surgery to stimulate intestinal peristalsis, to minimize occurrence of paralytic ileus, for inadequate intestinal tone causing abdominal distention, and to treat paralytic ileus.

Besides the possibility of hypersensitivity reaction, SIGMA PANTOTHENATE is relatively well tolerated and free from adverse reactions. Large doses may cause diarrhea.

Elevated carbamazepine levels occur when cefixime (SI-FIXIM) is coadministered. When given with warfarin / anticoagulants, the prothrombin time is elevated.

Absorption of paracetamol from NIMCET Plus is increased by concomitant metoclopramide, and such other agents. Probenecid can decrease it's clearance, whilst cholestyramine diminishes absorption of paracetamol (in NIMCET Plus) when coadministered.

Oral: 1 SIGMA PANTOTHENATE Tab od daily, or as prescribed.

Injection: 1-2 ml SIGMA PANTOTHENATE Inj IM / IV once or twice daily, or as prescribed.